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Are there any long term serious to take ibuprofen on a regular basis?

I take ibuprofen generic probably three times a week (usually 3 pills at once), usually only for headaches or minor aches and pains. I really not need to take such pains are not so bad, but I prefer headache not minor. I'm curious whether this use of ibuprofen can cause serious long term problems for my health? I would appreciate responses by medical professionals or scientists, preferably supported by studies and / or experience firsthand. In other words, I do not seek what he said a friend or something you think which may have once read in People magazine.

Yes, both first responders are correct. Nasidi long-term use can cause gastritis, which leads May stomach bleeding and anemia. Intersitial nephrite (a type of kidney disease) is another common complication. ,, Retention Hypertension water and angioedema are others.